Hydroxyurea-Induced Interstitial Pneumonitis

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Hydroxyurea-Induced Interstitial Pneumonitis: A Rare Clinical Entity

INTRODUCTION Hydroxyurea is a cytoreductive agent indicated in the treatment of variety of malignant and nonmalignant conditions.1 It generally is well tolerated with a side effect profile including bone marrow suppression, gastrointestinal, cutaneous manifestations, and fever.2 We present a case of hydroxyurea-induced interstitial pneumonitis manifesting with symptoms of progressively worsenin...

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Amiodarone-induced interstitial pneumonitis.

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Sirolimus induced granulomatous interstitial pneumonitis

OBJECTIVES Report a case of sirolimus induced granulomatous pneumonitis. BACKGROUND Sirolimus is used in clinical transplantation as an immunosuppressive agent. Pulmonary toxicity does occur, but only a few cases of sirolimus associated granulomatous interstitial pneumonitis have been reported. METHODS Case report and literature review. RESULTS This 53-year-old woman with ESRD from polycy...

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Chlorambucil is an alkylating agent commonly used in treatment of chronic lymphocytic leukemia (CLL). We report a case of interstitial pneumonitis developing in an 83-year-old man 1.5 months after completing a six-month course of chlorambucil for CLL. The interstitial pneumonitis responded to therapy with prednisone. We performed a systematic review of literature and identified 13 other case re...

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My colleague and collaborator, the late Edgar G. Harrison, Jr., M.D., was of the opinion that “desquamation” was a fundamental phenomenon in the spectrum of usual interstitial pneumonitis. In our report’ on classic interstitial pneumonitis-flbrosis, we found that almost two-thirds of our biopsies revealed this finding. Harrison believed that the designation, “desquamative interstitial pneurnoni...

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ژورنال

عنوان ژورنال: Kansas Journal of Medicine

سال: 2019

ISSN: 1948-2035

DOI: 10.17161/kjm.v10i2.8653